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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IREB2
All Species:
43.94
Human Site:
S821
Identified Species:
69.05
UniProt:
P48200
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48200
NP_004127.1
963
105047
S821
P
K
T
I
H
F
P
S
G
Q
T
L
D
V
F
Chimpanzee
Pan troglodytes
XP_523125
963
104993
S821
P
K
T
I
H
F
P
S
G
Q
T
L
D
V
F
Rhesus Macaque
Macaca mulatta
XP_001107837
964
105069
S822
P
K
T
I
H
F
P
S
G
Q
T
L
D
V
F
Dog
Lupus familis
XP_532364
964
105327
S822
P
K
T
I
H
F
P
S
G
Q
T
L
D
V
F
Cat
Felis silvestris
Mouse
Mus musculus
Q811J3
963
104918
S821
P
K
T
I
H
F
P
S
G
Q
T
L
D
V
F
Rat
Rattus norvegicus
Q62751
963
104783
S821
P
K
T
I
H
F
P
S
G
Q
T
L
D
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513243
1011
110449
S869
P
K
T
I
H
F
P
S
G
Q
T
L
D
V
F
Chicken
Gallus gallus
Q5ZLQ4
965
105344
S823
P
K
T
I
H
F
P
S
G
Q
T
L
D
V
F
Frog
Xenopus laevis
Q6NTP2
955
104418
S813
P
K
T
I
H
L
P
S
G
Q
T
M
D
V
F
Zebra Danio
Brachydanio rerio
XP_001341791
896
98752
T753
P
K
T
L
H
I
P
T
G
Q
T
L
D
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524303
899
98560
S756
P
R
T
V
H
I
P
S
Q
E
E
L
D
I
F
Honey Bee
Apis mellifera
XP_392993
890
98796
D756
K
E
E
M
D
V
F
D
A
A
E
L
Y
I
K
Nematode Worm
Caenorhab. elegans
Q23500
887
96642
A754
E
L
D
I
F
D
A
A
Q
K
Y
K
D
A
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42560
898
98134
R765
F
D
A
A
M
K
Y
R
N
E
G
R
D
T
I
Baker's Yeast
Sacchar. cerevisiae
P19414
778
85350
R648
P
D
T
A
R
D
Y
R
D
Q
G
I
K
W
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.1
92.5
N.A.
93.6
93.8
N.A.
84.4
82.1
68.5
62.9
N.A.
54.5
55.5
52.3
N.A.
Protein Similarity:
100
99.6
99.6
96.8
N.A.
96.6
97.1
N.A.
89.9
91.1
81
77
N.A.
72.4
71.8
67.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
86.6
80
N.A.
53.3
6.6
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
93.3
N.A.
80
26.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.1
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.5
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
14
0
0
7
7
7
7
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
14
7
0
7
14
0
7
7
0
0
0
87
0
0
% D
% Glu:
7
7
7
0
0
0
0
0
0
14
14
0
0
0
0
% E
% Phe:
7
0
0
0
7
54
7
0
0
0
0
0
0
0
74
% F
% Gly:
0
0
0
0
0
0
0
0
67
0
14
0
0
0
7
% G
% His:
0
0
0
0
74
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
67
0
14
0
0
0
0
0
7
0
14
7
% I
% Lys:
7
67
0
0
0
7
0
0
0
7
0
7
7
0
7
% K
% Leu:
0
7
0
7
0
7
0
0
0
0
0
74
0
0
0
% L
% Met:
0
0
0
7
7
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
80
0
0
0
0
0
74
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
14
74
0
0
0
0
0
% Q
% Arg:
0
7
0
0
7
0
0
14
0
0
0
7
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% S
% Thr:
0
0
80
0
0
0
0
7
0
0
67
0
0
7
0
% T
% Val:
0
0
0
7
0
7
0
0
0
0
0
0
0
67
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
0
0
0
0
0
14
0
0
0
7
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _